An FDA safety review found the potential for increased risk of heart rhythm problems, called arrhythmias, in patients with heart disease who are taking the seizure and mental health medicine Lamictal (lamotrigine).These studies began when the FDA received reports of abnormal electrocardiographic (ECG) findings among individuals taking this medication. In some cases, problems including chest pain, loss of consciousness, and cardiac arrest occurred. The FDA is currently evaluating whether other medicines in the same drug class have similar effects on the heart.